Article
Deletion of the Mycobacterium tuberculosis resuscitation-promoting factor Rv1009 gene results in delayed reactivation from chronic tuberculosis.
Infection and immunity - 1 May 2006
Tufariello JoAnn M, Mi Kaixia, Xu Jiayong, Manabe Yukari C, Kesavan Anup K, Drumm Joshua, Tanaka Kathryn, Jacobs William R, Chan John
Abstract excerpt
Approximately one-third of the human population is latently infected with Mycobacterium tuberculosis, comprising a critical reservoir for disease reactivation. Despite the importance of latency in maintaining M. tuberculosis in the human population, little is known about the mycobacterial factors that regulate persistence and reactivation. Previous in vitro studies have implicated a family of five related M....
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