Article
The human Cyr61 gene is a transcriptional target of transforming growth factor beta in cancer cells.
Cancer letters - 8 Feb 2007
Bartholin Laurent, Wessner Lisa L, Chirgwin John M, Guise Theresa A
Abstract excerpt
Cyr61 is a multifunctional protein that can stimulate angiogenesis and tumor growth. Its expression by many cancers and breast cancers increases with tumor grade. Cyr61 is closely related to connective tissue growth factor, CTGF. Both proteins regulate skeletal development, suggesting that they c...
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