A functional polymorphism in the CYR61 (IGFBP10) gene is associated with prostate cancer risk.

doi:10.1038/pcan.2012.41

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A functional polymorphism in the CYR61 (IGFBP10) gene is associated with prostate cancer risk.

Prostate cancer and prostatic diseases - 1 Mar 2013

Tao L, Chen J, Zhou H, Qin C, Li P, Cao Q, Li J, Ju X, Zhu C, Wang M, Zhang Z, Shao P, Yin C

Abstract excerpt

BACKGROUND: CYR61 (cysteine-rich protein 61, also named IGFBP10) is a secreted signaling molecule that promotes angiogenesis and tumor growth. The goal of this study is to determine whether a functional polymorphism in the promoter region of the CYR61 gene (rs3753793) is associated with prostate cancer (PCa) risk and gene expression in Chinese patients. METHODS: A total of 665 patients diagnosed with PCa and 703...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Grading

Share to Neoplasm Staging

Share to Promoter Regions, Genetic

Share to Prostatic Neoplasms

Share to Real-Time Polymerase Chain Reaction

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to RNA, Messenger

Source

Open in PubMed

Identifiers

PMID: 23045290
DOI: 10.1038/pcan.2012.41

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A functional polymorphism in the CYR61 (IGFBP10) gene is associated with prostate cancer risk.PMID 23045290Read ↗

The human Cyr61 gene is a transcriptional target of transforming growth factor beta in cancer cells.Semantic proximity Read ↗

Polymorphisms of the CYR61 gene in patients with acute myeloid leukemia in a Han Chinese population.Semantic proximity Read ↗

PER3 polymorphisms and their association with prostate cancer risk in Japanese men.Semantic proximity Read ↗

Evaluation of functional genetic variants at 6q25.1 and risk of breast cancer in a Chinese population.Semantic proximity Read ↗

Susceptibility loci associations with prostate cancer risk in northern Chinese men.Semantic proximity Read ↗

Association of HPC2/ELAC2 polymorphism with prostate cancer risk in a Japanese population.Semantic proximity Read ↗

Polymorphisms at long non-coding RNAs and prostate cancer risk in an eastern Chinese population.Semantic proximity Read ↗

rs2274911 polymorphism in GPRC6A associated with serum E2 and PSA in a Southern Chinese male population.Semantic proximity Read ↗

Clinical significance of runt-related transcription factor 1 polymorphism in prostate cancer.Semantic proximity Read ↗

Functional variants inPXRare associated with colorectal cancer susceptibility in Chinese populations.Semantic proximity Read ↗

CXCL12 G801A polymorphism is a risk factor for sporadic prostate cancer susceptibility.Semantic proximity Read ↗

IGF-1 Regulates Cyr61 Induced Breast Cancer Cell Proliferation and InvasionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.