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Article

hNaf1 is required for accumulation of human box H/ACA snoRNPs, scaRNPs, and telomerase

6 Apr 2006

Abstract excerpt

The human telomerase ribonucleoprotein particle (RNP) shares with box H/ACA small Cajal body (sca)RNPs and small nucleolar (sno)RNPs the proteins dyskerin, hGar1, hNhp2, and hNop10. How dyskerin, hGar1, hNhp2, and hNop10 assemble with box H/ACA scaRNAs, snoRNAs, and the RNA component of telomerase (hTR) in vivo remains unknown. In yeast, Naf1p interacts with H/ACA snoRNP proteins and may promote assembly of Cbf5p...

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Identifiers

PMID: 16601202
DOI: 10.1261/rna.2344106

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