Splicing of the Drosophila P element ORF2-ORF3 intron is inhibited in a human cell extract.

doi:10.1016/0925-4773(91)90042-5

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Article

Splicing of the Drosophila P element ORF2-ORF3 intron is inhibited in a human cell extract.

Mechanisms of development - 1 Aug 1991

Tseng J C, Zollman S, Chain A C, Laski F A

Abstract excerpt

P element transposition in Drosophila melanogaster is regulated by germline-specific splicing of the P element ORF2-ORF3 intron. This regulation has been shown to depend on a cis-acting sequence located in the exon 12-31 bases from the 5' splice site. Mutations within this sequence disrupt the re...

Topics

Animals
Base Sequence
Cell Extracts
DNA Transposable Elements
Drosophila
Exons
HeLa Cells
Humans
Introns
Molecular Sequence Data
Mutation
Peptides
RNA Splicing
RNA, Messenger
Transcriptional Activation
Ultraviolet Rays

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