Stepwise Decrease in Moxifloxacin Susceptibility amongst Clinical Isolates of Multidrug-Resistant <i>Mycobacterium tuberculosis:</i> Correlation with Ofloxacin Susceptibility

Abstract excerpt

To study the effectiveness of moxifloxacin (MOX) against multidrug-resistant (MDR) Mycobacterium tuberculosis (MTB), in vitro drug susceptibility tests on MOX and ofloxacin (OFX) using the MGIT system against 132 nonduplicate MDR MTB isolates (108 OFX-sensitive and 24 OFX-resistant) were performed. Eleven OFX-resistant non-MDR MTB isolates were also included. All strains that were susceptible to OFX were shown to...

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