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Association of <i>gyrA/B</i> mutations and resistance levels to fluoroquinolones in clinical isolates of <i>Mycobacterium tuberculosis</i>

1 Jan 2014

Abstract excerpt

To evaluate the association between mutations in the genes gyrA/B and resistance levels to fluoroquinolones in clinical isolates of Mycobacterium tuberculosis, a total of 80 ofloxacin-resistant isolates collected in 2009 by the Shanghai Municipal Centers for Disease Control and Prevention were studied. The minimum inhibitory concentration (MIC) of ofloxacin, moxifloxacin and gatifloxacin for each isolate was...

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PMID: 26038513
DOI: 10.1038/emi.2014.21

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