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Article

Molecular cloning and biochemical characterization of a truncated, secreted member of the human family of Ca2+-activated Cl− channels

1 Mar 1999

Abstract excerpt

A novel family of chloride channel proteins has recently been discovered including two bovine (Lu-ECAM-1, bCLCA1), one murine (mCLCA1), and two human (hCLCA1 and hCLCA2) members. Here, we describe the cloning, expression, and molecular characterization of a truncated human homolog, tentatively named hCLCA3. It was cloned from a human spleen cDNA library and is expressed in numerous tissues including lung,...

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PMID: 10095065
DOI: 10.1016/s0167-4781(99)00008-1

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