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Article

J-Resolved 1H NMR 1D-Projections for Large-Scale Metabolic Phenotyping Studies: Application to Blood Plasma Analysis.

Analytical chemistry - 7 Nov 2017

Rodriguez-Martinez Andrea, Posma Joram M, Ayala Rafael, Harvey Nikita, Jimenez Beatriz, Neves Ana L, Lindon John C, Sonomura Kazuhiro, Sato Taka-Aki, Matsuda Fumihiko, Zalloua Pierre, Gauguier Dominique, Nicholson Jeremy K, Dumas Marc-Emmanuel

Abstract excerpt

1H nuclear magnetic resonance (NMR) spectroscopy-based metabolic phenotyping is now widely used for large-scale epidemiological applications. To minimize signal overlap present in 1D 1H NMR spectra, we have investigated the use of 2D J-resolved (JRES) 1H NMR spectroscopy for large-scale phenotyping studies. In particular, we have evaluated the use of the 1D projections of the 2D JRES spectra (pJRES), which...

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PMID: 28937204
DOI: 10.1021/acs.analchem.7b02374

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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