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Article

Influence of mutation type on clinical expression of Leber hereditary optic neuropathy.

American journal of ophthalmology - 1 Apr 2006

Spruijt Liesbeth, Kolbach Dinanda N, de Coo Rene F, Plomp Astrid S, Bauer Noel J, Smeets Hubertus J, de Die-Smulders Christine E M

Abstract excerpt

PURPOSE: The aim of this research was to determine the molecular factors of influence on the clinical expression of Leber hereditary optic neuropathy (LHON), which might aid in counseling LHON patients and families. The prevalence of LHON in the Dutch population was determined. DESIGN: Observational, retrospective population cohort study. METHODS: The clinical characteristics of LHON patients of 25 families,...

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Identifiers

PMID: 16564802
DOI: 10.1016/j.ajo.2005.11.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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