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Article

Bile acid synthesis in cultured human hepatoblastoma cells.

1 Sept 1991

Abstract excerpt

Biosynthetic pathways to bile acids have been studied in HepG2 cells, a well-differentiated human hepatoblastoma cell line. Cholesterol metabolites, in total 29, were isolated from culture media and cells by liquid-solid extraction and anion-exchange chromatography and were identified by gas-liquid chromatography-mass spectrometry. The production rates/concentrations of cholic acid (CA) and chenodeoxycholic acid...

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PMID: 1655725
DOI: 10.1016/s0021-9258(18)55193-0

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