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Evaluation of real-time PCR for diagnosis of Bordetella pertussis infection

23 Mar 2006

Abstract excerpt

BACKGROUND: Nucleic acid amplification of the IS481 region by PCR is more sensitive than culture for detection and diagnosis of Bordetella pertussis but the assay has known cross-reactivity for Bordetella holmesii and its use as a routine diagnostic assay has not been widely evaluated. METHODS: The objectives of this study were: 1) to assess the diagnostic utility of real-time IS481 PCR by comparison of results...

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PMID: 16556317
DOI: 10.1186/1471-2334-6-62

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