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Article

Genetics of papillary thyroid cancer initiation: implications for therapy.

Transactions of the American Clinical and Climatological Association - 1 Jan 2005

Fagin James A

Abstract excerpt

Papillary thyroid cancers are the most common thyroid malignancy. They usually carry a favorable prognosis, although patients with invasive or metastatic tumors that no longer trap radioiodine do less well. There is mounting experimental support for a central role of mutations leading to constitutive activation of MAP kinase effectors in the pathogenesis ofthis disease. Thus activating mutations of the tyrosine...

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Topics

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Share to Carcinoma, Papillary
Share to RET gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasms, Radiation-Induced

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Source

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Identifiers

PMID: 16555619
PMCID: PMC1473144

Genes

BRAF
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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