Article
Genetics and epigenetics of sporadic thyroid cancer.
Molecular and cellular endocrinology - 5 Apr 2014
Vu-Phan Dang, Koenig Ronald J
Abstract excerpt
Thyroid carcinoma is the most common endocrine malignancy, and although the disease generally has an excellent prognosis, therapeutic options are limited for patients not cured by surgery and radioiodine. Thyroid carcinomas commonly contain one of a small number of recurrent genetic mutations. The identification and study of these mutations has led to a deeper understanding of the pathophysiology of this disease...
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