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Article

Trypanosoma cruzi mitochondrial maxicircles display species- and strain-specific variation and a conserved element in the non-coding region.

BMC genomics - 22 Mar 2006

Westenberger Scott J, Cerqueira Gustavo C, El-Sayed Najib M, Zingales Bianca, Campbell David A, Sturm Nancy R

Abstract excerpt

BACKGROUND: The mitochondrial DNA of kinetoplastid flagellates is distinctive in the eukaryotic world due to its massive size, complex form and large sequence content. Comprised of catenated maxicircles that contain rRNA and protein-coding genes and thousands of heterogeneous minicircles encoding small guide RNAs, the kinetoplast network has evolved along with an extreme form of mRNA processing in the form of...

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Identifiers

PMID: 16553959
DOI: 10.1186/1471-2164-7-60
PMCID: PMC1559615

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Source receipt: pubmed, retrieved 7 Sept 2026.

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