Article
Isolation of mouse mammary epithelial progenitor cells with basal characteristics from the Comma-Dbeta cell line.
Developmental biology - 15 May 2006
Deugnier Marie-Ange, Faraldo Marisa M, Teulière Jérôme, Thiery Jean Paul, Medina Daniel, Glukhova Marina A
Abstract excerpt
A mouse mammary epithelial cell line with morphogenetic properties in vivo, Comma-Dbeta, was used to isolate and to characterize mammary progenitor cells. We found that a homogeneous cell population expressing high surface levels of stem cell antigen 1 (Sca-1) was able to give rise in vivo to ductal and alveolar structures comprising luminal secretory and basal myoepithelial cells. Unlike the Sca-1(high), the...
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