[Genes in Alzheimer's disease].

Abstract excerpt

INTRODUCTION: Alzheimer's disease (AD) is the most frequent degenerative dementia among the elderly population. Families that have an autosomal dominant pattern for AD constitute about 13% of early cases (< or = 65 years) and less than 0.01% of the total number of patients. DEVELOPMENT: Molecular analysis of families with early onset AD has made it possible to identify mutations in three different genes that are...

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