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Article

Human T-lymphotropic virus type 1 mitochondrion-localizing protein p13(II) is required for viral infectivity in vivo.

Journal of virology - 1 Apr 2006

Hiraragi Hajime, Kim Seung-Jae, Phipps Andrew J, Silic-Benussi Micol, Ciminale Vincenzo, Ratner Lee, Green Patrick L, Lairmore Michael D

Abstract excerpt

Human T-lymphotropic virus type 1 (HTLV-1), the etiological agent of adult T-cell leukemia, encodes unique regulatory and accessory proteins in the pX region of the provirus, including the open reading frame II product p13(II). p13(II) localizes to mitochondria, binds farnesyl pyrophosphate synthetase, an enzyme involved in posttranslational farnesylation of Ras, and alters Ras-dependent cell signaling and...

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Identifiers

PMID: 16537614
DOI: 10.1128/JVI.80.7.3469-3476.2006
PMCID: PMC1440407

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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