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Article

Glaucomatous outflow pathway and oxidative stress.

Experimental eye research - 1 Mar 2007

Saccà Sergio Claudio, Izzotti Alberto, Rossi Pietro, Traverso Carlo

Abstract excerpt

Oxidative free radicals and reactive oxygen species (ROS) are able to affect the cellularity of the human trabecular meshwork (HTM). These findings suggest that intraocular pressure increase, which characterises most glaucomas, is related to oxidative degenerative processes affecting the HTM and specifically its endothelial cells. Much evidence indicates that in this region ROS play a fundamental pathogenic role...

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Identifiers

PMID: 17196589
DOI: 10.1016/j.exer.2006.10.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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