Article
NG2 proteoglycan-expressing microglia as multipotent neural progenitors in normal and pathologic brains.
Glia - 1 May 2006
Yokoyama Akiko, Sakamoto Aiko, Kameda Kenji, Imai Yoshinori, Tanaka Junya
Abstract excerpt
Rat primary microglia (MG) acquired a multipotent property to give rise to neuroectodermal cells through two-step culture in 10 and 70% serum-supplemented media for 5 days. Such multipotent MG, called promicroglioblasts (ProMGBs), formed cell aggregates, which generated cells with neuroectodermal phenotypes shortly after their transfer into serum-free medium. As revealed by immunohistochemistry, there were a few...
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