Article
The effect of 5-hydroxytryptamine 3A and 3B receptor genes on nausea induced by paroxetine.
The pharmacogenomics journal - 1 Jan 2000
Sugai T, Suzuki Y, Sawamura K, Fukui N, Inoue Y, Someya T
Abstract excerpt
We investigated the effect of 5-hydroxytryptamine 3A and 3B receptor (HTR3A and HTR3B) gene polymorphisms on nausea induced by paroxetine in Japanese psychiatric patients. Blood samples were collected from 78 individuals after at least 2 weeks treatment with the same daily dose of paroxetine. The patients visited every 2 weeks and the paroxetine dose was changed in response to their clinical symptoms. Nausea was...
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