Article
Respective clustering of unfavorable and favorable cytogenetic clones in myelofibrosis with myeloid metaplasia with homozygosity for JAK2(V617F) and response to erythropoietin therapy.
Cancer - 15 Apr 2006
Tefferi Ayalew, Strand Jacob J, Lasho Terra L, Elliott Michelle A, Li Chin-Yang, Mesa Ruben A, Dewald Gordon W
Abstract excerpt
BACKGROUND: Patients who have myelofibrosis with myeloid metaplasia (MMM) display recurrent, albeit nonspecific cytogenetic abnormalities that are diverse prognostically. For the current study, the authors explored the relation between specific cytogenetic clones and JAK2(V617F) mutational status in patients with MMM and the effects on treatment response to erythropoietin (Epo). METHODS: Concomitantly collected...
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