Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A reappraisal of complete mtDNA variation in East Asian families with hearing impairment.

Human genetics - 1 Jun 2006

Yao Yong-Gang, Salas Antonio, Bravi Claudio M, Bandelt Hans-Jürgen

Abstract excerpt

In a number of recent studies, we summarized the obvious errors and shortcomings that can be spotted in many (if not most) mitochondrial DNA (mtDNA) data sets published in medical genetics. We have reanalyzed here the complete mtDNA genome data published in various recent reports of East Asian families with hearing impairment, using a phylogenetic approach, in order to demonstrate the persistence of lab-specific...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asia, Eastern
Share to DNA, Mitochondrial
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hearing Loss

Share to Mitochondria

Share to Polymorphism, Single Nucleotide

Share to Selection Bias

Source

Identifiers

PMID: 16528519
DOI: 10.1007/s00439-006-0154-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A reappraisal of complete mtDNA variation in East Asian families with hearing impairment.PMID 16528519Read ↗

Updating the East Asian mtDNA phylogeny: a prerequisite for the identification of pathogenic mutations.Semantic proximity Read ↗

Mitochondrial haplotype and phenotype of 13 Chinese families may suggest multi-original evolution of mitochondrial C1494T mutation.Semantic proximity Read ↗

Extremely low penetrance of deafness associated with the mitochondrial 12S rRNA T1095C mutation in three Chinese families.Semantic proximity Read ↗

Coexistence of mitochondrial 12S rRNA C1494T and CO1/tRNA(Ser(UCN)) G7444A mutations in two Han Chinese pedigrees with aminoglycoside-induced and non-syndromic hearing loss.Semantic proximity Read ↗

Very low penetrance of hearing loss in seven Han Chinese pedigrees carrying the deafness-associated 12S rRNA A1555G mutation.Semantic proximity Read ↗

Prevalence and clinical features of the mitochondrial m.1555A>G mutation in Taiwanese patients with idiopathic sensorineural hearing loss and association of haplogroup F with low penetrance in three families.Semantic proximity Read ↗

Mitochondrial haplotypes may modulate the phenotypic manifestation of the deafness-associated 12S rRNA 1555A>G mutation.Semantic proximity Read ↗

Extremely low penetrance of hearing loss in four Chinese families with the mitochondrial 12S rRNA A1555G mutation.Semantic proximity Read ↗

Variants in mitochondrial tRNAGlu, tRNAArg, and tRNAThr may influence the phenotypic manifestation of deafness-associated 12S rRNA A1555G mutation in three Han Chinese families with hearing loss.Semantic proximity Read ↗

Audiological and genetic features of the mtDNA mutations.Semantic proximity Read ↗

Heteroplasmy levels of mtDNA1555A>G mutation is positively associated with diverse phenotypes and mutation transmission in a Chinese family.Semantic proximity Read ↗

'Progress' renders detrimental an ancient mitochondrial DNA genetic variant.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.