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Stress oxydant et vieillissement

1 Mar 2006

Abstract excerpt

A number of theories have attempted to account for ageing processes in various species. Following the << rate of living >> theory of Pearl, Harman suggested fifty years ago that the accumulation of oxidants could explain the alteration of physical and cognitive functions with ageing. Oxygen metabolism leads to reactive species, including free radicals, which tend to oxidize surrounding molecules such as DNA,...

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PMID: 16527207
DOI: 10.1051/medsci/2006223266

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