Article
Free radical theory of aging.
Current opinion in clinical nutrition and metabolic care - 1 Jan 2002
Biesalski Hans K
Abstract excerpt
The free radical theory of the aging process is based on the hypothesis that with increasing age, mutations of the mitochondrial DNA will accumulate and will at least lead to a loss of function with subsequent acceleration of cell death. Even if this theory is widely accepted, the reactive-oxygen-species-induced mutations of mitochondrial DNA, the accumulation of mitochondrial DNA and the role of antioxidants are...
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