Article
XpsE oligomerization triggered by ATP binding, not hydrolysis, leads to its association with XpsL.
The EMBO journal - 5 Apr 2006
Shiue Sheng-Jie, Kao Ko-Min, Leu Wei-Ming, Chen Ling-Yun, Chan Nei-Li, Hu Nien-Tai
Abstract excerpt
GspE belongs to a secretion NTPase superfamily, members of which are involved in type II/IV secretion, type IV pilus biogenesis and DNA transport in conjugation or natural transformation. Predicted to be a cytoplasmic protein, GspE has nonetheless been shown to be membrane-associated by interacting with the N-terminal cytoplasmic domain of GspL. By taking biochemical and genetic approaches, we observed that ATP...
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