Article
Nucleotide oligomerization domain 2 (Nod2) is not involved in the pattern recognition of Candida albicans.
Clinical and vaccine immunology : CVI - 1 Mar 2006
van der Graaf Chantal A A, Netea Mihai G, Franke Barbara, Girardin Stephen E, van der Meer Jos W M, Kullberg Bart Jan
Abstract excerpt
Nucleotide-binding oligomerization domain 2 (Nod2) pathways are known to interact with Toll-like receptor 2 (TLR2) and TLR4, which are pattern recognition receptors for Candida albicans. We observed that the prevalence of Nod2 polymorphisms was not increased in patients with Candida infections. Candida-induced cytokine production in individuals with Nod2 polymorphisms was unaffected. We conclude that Nod2 is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.