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Article

Lack of evidence of premature atherosclerosis in untreated severe isolated growth hormone (GH) deficiency due to a GH-releasing hormone receptor mutation.

The Journal of clinical endocrinology and metabolism - 1 Jun 2006

Menezes Oliveira Joselina Luzia, Marques-Santos Celi, Barreto-Filho José Augusto, Ximenes Filho Roberto, de Oliveira Britto Allan Valadão, Oliveira Souza Anita Hermínia, Prado Clarisse Miranda, Pereira Oliveira Carla Raquel, Pereira Rossana Maria C, Ribeiro Vicente Tábita de Almeida, Farias Catarine Teles, Aguiar-Oliveira Manuel Hermínio, Salvatori Roberto

Abstract excerpt

BACKGROUND: GH deficiency (GHD) acquired at adult age as a result of pathological processes of the pituitary gland or the hypothalamus causes changes that are associated with worsening cardiovascular risk. They include increase in abdominal obesity, total and low- density lipoprotein cholesterol,...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Neuropeptide

Share to Receptors, Pituitary Hormone-Regulating Hormone

Source

Identifiers

PMID: 16522693
DOI: 10.1210/jc.2005-2571

Genes

GHRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16522693-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Lack of evidence of premature atherosclerosis in untreated severe isolated growth hormone (GH) deficiency due to a GH-releasing hormone receptor mutation.PMID 16522693Read ↗

Lifetime, untreated isolated GH deficiency due to a GH-releasing hormone receptor mutation has beneficial consequences on bone status in older individuals, and does not influence their abdominal aorta calcification.Semantic proximity Read ↗

MECHANISMS IN ENDOCRINOLOGY: The multiple facets of GHRH/GH/IGF-I axis: lessons from lifetime, untreated, isolated GH deficiency due to a GHRH receptor gene mutation.Semantic proximity Read ↗

Lipid profiles in untreated severe congenital isolated growth hormone deficiency through the lifespan.Semantic proximity Read ↗

[Long time consequences of the growth hormone deficiency].Semantic proximity Read ↗

Longevity in untreated congenital growth hormone deficiency due to a homozygous mutation in the GHRH receptor gene.Semantic proximity Read ↗

[Growth or somatotrophic hormone: new perspectives in isolated GH deficiency after description of the mutation in the GHRH receptor gene in individuals of Itabaianinha County, Brazil].Semantic proximity Read ↗

Heterozygosity for a mutation in the growth hormone-releasing hormone receptor gene does not influence adult stature, but affects body composition.Semantic proximity Read ↗

Metabolic effects of growth hormone (GH) replacement in children and adolescents with severe isolated GH deficiency due to a GHRH receptor mutation.Semantic proximity Read ↗

Absence of GH-releasing hormone (GHRH) mutations in selected patients with isolated GH deficiency.Semantic proximity Read ↗

IGF-I bioavailability in congenital isolated growth hormone deficiency.Semantic proximity Read ↗

Abnormal metabolic phenotype in middle-aged GH-deficient adults despite long-term recombinant human GH replacement.Semantic proximity Read ↗

Reduced Longevity in Untreated Patients with Isolated Growth Hormone DeficiencySemantic proximity Read ↗

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