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Article

Metabolic effects of growth hormone (GH) replacement in children and adolescents with severe isolated GH deficiency due to a GHRH receptor mutation.

Clinical endocrinology - 1 Apr 2007

Gleeson Helena, Barreto Elenilde S de A, Salvatori Roberto, Costa Liana, Oliveira Carla R P, Pereira Rossana M C, Clayton Peter, Aguiar-Oliveira Manuel H

Abstract excerpt

BACKGROUND: The interpretation of the true effect of GH replacement therapy (GHRT) on metabolic status in GH deficiency (GHD) is often complicated by differing aetiologies of GHD and by the presence of additional hormone deficits. OBJECTIVE: To study the growth and response of the lipid profile and body composition to GHRT in a cohort of children with the same mutation in the GHRH receptor gene. Design Nine...

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Source

Identifiers

PMID: 17371461
DOI: 10.1111/j.1365-2265.2007.02753.x

Genes

GHRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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