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Article

Characterization of CD4+CD25+ regulatory T cells in patients treated with high-dose interleukin-2 for metastatic melanoma or renal cell carcinoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Mar 2006

Cesana Giovanni C, DeRaffele Gail, Cohen Seth, Moroziewicz Dorota, Mitcham Josephine, Stoutenburg John, Cheung Ken, Hesdorffer Charles, Kim-Schulze Seunghee, Kaufman Howard L

Abstract excerpt

PURPOSE: To characterize the number and functional status of CD4+CD25+ regulatory T cells (Tregs) in patients with metastatic melanoma (MM) and renal cell carcinoma (RCC) treated with high-dose bolus interleukin-2 (IL-2). PATIENTS AND METHODS: Patients with MM or RCC treated with high-dose bolus IL-2 (600,000 IU/kg every 8 hours) at a single center provided pre- and post-treatment whole blood specimens....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16505437
DOI: 10.1200/JCO.2005.03.6830

Genes

CCR7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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