Article
Lipid rafts remodeling in estrogen receptor-negative breast cancer is reversed by histone deacetylase inhibitor.
Molecular cancer therapeutics - 1 Feb 2006
Ostapkowicz Anna, Inai Kunihiro, Smith Leia, Kreda Silvia, Spychala Jozef
Abstract excerpt
Recently, we have found dramatic overexpression of ecto-5'-nucleotidase (or CD73), a glycosylphosphatidylinositol-anchored component of lipid rafts, in estrogen receptor-negative [ER-] breast cancer cell lines and in clinical samples. To find out whether there is a more general shift in expression profile of membrane proteins, we undertook an investigation on the expression of selected membrane and cytoskeletal...
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