Article
Association of the Met-196-Arg variation of human tumor necrosis factor receptor 2 (TNFR2) with paranoid schizophrenia.
Journal of molecular neuroscience : MN - 1 Mar 2011
Thabet Sihem, Ben Nejma Mouna, Zaafrane Ferid, Gaha Lotfi, Ben Salem Kamel, Romdhane Abdelaziz, Nour Mohamed, Jrad Besma Bel Hadj
Abstract excerpt
Research has provided strong evidence for oligodendrocyte and myelin-related genes dysfunction in schizophrenia. Several studies have suggested abnormalities in the expression of myelin-related genes including tumor necrosis factor receptor 2 (TNFR2) involved in the neurodegeneration and remyelination. In order to further assess the role of TNFR2 in schizophrenia, we examined a functional bi-allelic polymorphism...
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