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Article

Functional screening for proapoptotic genes by reverse transfection cell array technology.

Genomics - 1 May 2006

Mannherz Otto, Mertens Daniel, Hahn Meinhard, Lichter Peter

Abstract excerpt

Application of mathematical algorithms to sequenced whole genomes revealed a large number of predicted genes, requiring functional assays for their characterization in a high-throughput manner. Here, we report on the development of a screening assay, which is based on reverse transfection of cellular arrays and subsequent analysis of cell morphology to identify novel proapoptotic genes. Expression plasmids...

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PMID: 16503394
DOI: 10.1016/j.ygeno.2005.12.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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