Article
A novel MGST2 non-synonymous mutation in a Chinese pedigree with psoriasis vulgaris.
The Journal of investigative dermatology - 1 May 2006
Yan Kai-Lin, Zhang Xue-Jun, Wang Zhi-Min, Yang Sen, Zhang Guo-Long, Wang Jian, Xiao Feng-Li, Gao Min, Cui Yong, Chen Jian-Jun, Fan Xing, Sun Liang-Dan, Xia Qing, Zhang Kai-Yue, Niu Zhen-Min, Xu Shi-Jie, Tzschach Andreas, Ropers Hilger, Huang Wei, Liu Jian-Jun
Abstract excerpt
A balanced translocation was recently identified in a German psoriasis patient. One of the breakpoints was mapped immediately upstream of the microsomal glutathione S-transferase 2 (MGST2) gene, suggesting it as a candidate gene. Here, we report the identification of a novel non-synonymous mutation in MGST2 by a comprehensive sequence analysis of MGST2's coding region in Chinese psoriasis samples. We demonstrate...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.