Article
The association between GJB2 gene polymorphism and psoriasis: a verification study.
Archives of dermatological research - 1 Nov 2012
Liu Que-Ping, Wu Li-Sha, Li Fang-Fang, Liu Shuang, Su Juan, Kuang Ye-Hong, Chen Chen, Xie Xiao-Yun, Jiang Ming-Hao, Zhao Shuang, Chen Ming-Liang, Chen Xiang
Abstract excerpt
Psoriasis is a chronic inflammatory skin disease with multifactorial etiology. Connexin 26 (Cx26), an important gap junction protein, has been found highly expressed in plaques of psoriasis. Recently, genome wide association studies (GWAS) identified one new single nucleotide polymorphism (SNP) in GJB2 gene coding for Cx26 protein associated with psoriasis in Chinese Han population. In this paper, we verified the...
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