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Subtype Classification of Hepatocellular Adenoma

1 Jan 2010

Abstract excerpt

Hepatocellular adenomas (HCA) are rare benign tumours occurring mainly in women under oral contraceptives. HCA bleed frequently and transform rarely into hepatocellular carcinoma. Identification of genes recurrently mutated in HCA and good genotype/phenotype correlations provided the basis of a pathomolecular classification of different HCA subgroups, characterized using immunohistochemical markers. HNF1A-mutated...

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PMID: 20357450
DOI: 10.1159/000268406

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