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Article

Reduced virulence of an fliC mutant of Shiga-toxigenic Escherichia coli O113:H21.

Infection and immunity - 1 Mar 2006

Rogers Trisha J, Paton James C, Wang Hui, Talbot Ursula M, Paton Adrienne W

Abstract excerpt

The contribution of flagellin to the virulence of the O113:H21 Shiga-toxigenic Escherichia coli (STEC) strain 98NK2 was investigated in the streptomycin-treated mouse model. Groups of mice were challenged with either the wild-type STEC or a fliC deletion derivative thereof. There was no difference in the level of gut colonization by the two strains, but the fliC mutant was significantly less virulent than its...

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Identifiers

PMID: 16495575
DOI: 10.1128/IAI.74.3.1962-1966.2006
PMCID: PMC1418679

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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