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Article

Trophoblast Contact Deactivates Human Neutrophils

1 Mar 2006

Abstract excerpt

Trophoblasts are fetal epithelial cells that form an interface between mother and offspring. To evaluate their anti-inflammatory capacity, we tested the hypothesis that trophoblasts deactivate neutrophils using single-cell assays. Several biophysical (Ca2+ and NAD(P)H oscillation frequency) and physiological (oxidant production) markers of activated neutrophils revert to a nonactivated phenotype as activated...

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PMID: 16493081
DOI: 10.4049/jimmunol.176.5.3205

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