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Article

<i>Theileria parva</i> candidate vaccine antigens recognized by immune bovine cytotoxic T lymphocytes

21 Feb 2006

Abstract excerpt

East Coast fever, caused by the tick-borne intracellular apicomplexan parasite Theileria parva, is a highly fatal lymphoproliferative disease of cattle. The pathogenic schizont-induced lymphocyte transformation is a unique cancer-like condition that is reversible with parasite removal. Schizont-infected cell-directed CD8(+) cytotoxic T lymphocytes (CTL) constitute the dominant protective bovine immune response...

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PMID: 16492763
DOI: 10.1073/pnas.0511273103

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