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Article

Characterization of the gene encoding the polymorphic immunodominant molecule, a neutralizing antigen of Theileria parva

1 Aug 1995

Abstract excerpt

Theileria parva, a tick-transmitted protozoan parasite related to Plasmodium spp., causes the disease East Coast fever, an acute and usually fatal lymphoproliferative disorder of cattle in Africa. Previous studies using sera from cattle that have survived infection identified a polymorphic immunodominant molecule (PIM) that is expressed by both the infective sporozoite stage of the parasite and the intracellular...

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Identifiers

PMID: 7636202
DOI: 10.4049/jimmunol.155.3.1370

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Characterization of the gene encoding the polymorphic immunodominant molecule, a neutralizing antigen of Theileria parvaPMID 7636202Read ↗

Structure and sequence variation of the genes encoding the polymorphic, immunodominant molecule (PIM), an antigen of Theileria parva recognized by inhibitory monoclonal antibodies.Semantic proximity Read ↗

Analyses of genes encoding Theileria parva p104 and polymorphic immunodominant molecule (PIM) reveal evidence of the presence of cattle-type alleles in the South African T. parva population.Semantic proximity Read ↗

Analysis of p67 allelic sequences reveals a subtype of allele type 1 unique to buffalo-derived Theileria parva parasites from southern Africa.Semantic proximity Read ↗

Variant analysis of the sporozoite surface antigen gene reveals that asymptomatic cattle from wildlife-livestock interface areas in northern Tanzania harbour buffalo-derived T. parva.Semantic proximity Read ↗

Two Theileria parva CD8 T cell antigen genes are more variable in buffalo than cattle parasites, but differ in pattern of sequence diversity.Semantic proximity Read ↗

Analysis of p67 allelic sequences reveals a subtype of allele type 1 unique to buffalo-derived <i>Theileria parva</i> parasites from southern AfricaSemantic proximity Read ↗

Molecular evolution of a central region containing B cell epitopes in the gene encoding the p67 sporozoite antigen within a field population of Theileria parva.Semantic proximity Read ↗

Genes encoding two Theileria parva antigens recognized by CD8+ T-cells exhibit sequence diversity in South Sudanese cattle populations but the majority of alleles are similar to the Muguga component of the live vaccine cocktail.Semantic proximity Read ↗

Theileria parva antigens recognized by CD8+ T cells show varying degrees of diversity in buffalo-derived infected cell lines.Semantic proximity Read ↗

An unusual mosaic structure of the PIM gene of Theileria parva and its relationship to allelic diversity.Semantic proximity Read ↗

The African buffalo parasite Theileria. sp. (buffalo) can infect and immortalize cattle leukocytes and encodes divergent orthologues of Theileria parva antigen genesSemantic proximity Read ↗

Genetic and antigenic variation of the bovine tick-borne pathogen Theileria parva in the Great Lakes region of Central Africa.Semantic proximity Read ↗

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