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Article

Extensive polymorphism and evidence of immune selection in a highly dominant antigen recognized by bovine CD8 T cells specific for Theileria annulata.

Infection and immunity - 1 May 2011

MacHugh Niall D, Weir William, Burrells Alison, Lizundia Regina, Graham Simon P, Taracha Evans L, Shiels Brian R, Langsley Gordon, Morrison W Ivan

Abstract excerpt

Although parasite strain-restricted CD8 T cell responses have been described for several protozoa, the precise role of antigenic variability in immunity is poorly understood. The tick-borne protozoan parasite Theileria annulata infects leukocytes and causes an acute, often fatal lymphoproliferative disease in cattle. Building on previous evidence of strain-restricted CD8 T cell responses to T. annulata, this...

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Source

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Identifiers

PMID: 21300773
DOI: 10.1128/IAI.01285-10
PMCID: PMC3088144

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Source receipt: pubmed, retrieved 7 Sept 2026.

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