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Article

Relationship between genotype and enzyme activity of glutathione S-transferases M1 and P1 in Chinese.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences - 1 May 2006

Zhong Shi-long, Zhou Shu-Feng, Chen Xiao, Chan Sui Yung, Chan Eli, Ng Ka-Yun, Duan Wei, Huang Min

Abstract excerpt

Glutathione S-transferases (GSTs) are the major detoxifying Phase II enzyme for eliminating electrophilic compounds. Mutations in GSTM1, GSTP1 and GSTT1 in Caucasian and GSTA1 in Chinese have been found to reduce enzyme activity. However, data on the impact of common genetic polymorphisms of GSTM1 and GSTP1 on enzyme activity in Chinese is lacking. This study aimed to investigate the effect of common GSTP1 and...

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Identifiers

PMID: 16488119
DOI: 10.1016/j.ejps.2006.01.002

Genes

GSTP1
GSTM1
GSTA1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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