Article
Glycerol as a correlate of impaired glucose tolerance: dissection of a complex system by use of a simple genetic trait.
American journal of human genetics - 1 May 2000
Gaudet D, Arsenault S, Pérusse L, Vohl M C, St-Pierre J, Bergeron J, Després J P, Dewar K, Daly M J, Hudson T, Rioux J D
Abstract excerpt
Glycerol kinase (GK) represents the primary entry of glycerol into glucose and triglyceride metabolism. Impaired glucose tolerance (IGT) and hypertriglyceridemia are associated with an increased risk of diabetes mellitus and cardiovascular disease. The relationship between glycerol and the risk of IGT, however, is poorly understood. We therefore undertook the study of fasting plasma glycerol levels in a cohort of...
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