Deep sequencing of small RNA facilitates tissue and sex specific microRNA discovery in zebrafish

Abstract excerpt

Role of microRNAs in gene regulation has been well established. Though the number of genes appear to be equal between human and zebrafish, miRNAs detected in zebrafish (~247) is significantly low compared to human (~2000; miRBase Release 19). It appears that most of the miRNAs in zebrafish are yet to be discovered. Using next generation sequencing technology, we sequenced small RNAs from brain, gut, liver, ovary,...

Topics

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• Base Sequence
• Blotting, Northern
• Genetic Variation
• Models, Genetic
• Molecular Sequence Data
• Nucleic Acid Conformation
• Sequence Analysis, DNA
• Sequence Homology, Nucleic Acid

Identifiers and source

Literature Corpus work

945f5285-c232-50ae-b355-d44ad4357f32

DOI

10.1101/019760