Article
Gonadotropin-induced superovulation drives ovarian surface epithelia proliferation in CD1 mice.
Endocrinology - 1 May 2006
Burdette Joanna E, Kurley Sarah J, Kilen Signe M, Mayo Kelly E, Woodruff Teresa K
Abstract excerpt
The ovarian surface epithelium (OSE) is a monolayer of cells that surround the ovary and accommodate repeated tear and repair in response to ovulation. OSE cells are thought to be the progenitors of 90% of ovarian cancers. Currently, the total amount of proliferation of the OSE has not been reported in response to one ovulatory event. In this study, proliferation of the OSE was quantified in response to...
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