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Article

Determination of the amino acid residues required for the activity of the anti-rhizobial peptide antibiotic trifolitoxin.

Journal of applied microbiology - 1 Mar 2006

Scupham A J, Triplett E W

Abstract excerpt

AIMS: The first aim was to determine those amino acid residues required for the biological activity of the potent peptide antibiotic, trifolitoxin (TFX). The second aim was to determine the concentrations of TFX1 and TFX2 that cause 50% inhibition of bacterial growth (Ki), the two predominant isomeric forms of TFX made by Rhizobium. METHODS AND RESULTS: Site-directed mutagenesis of tfxA was used to produce...

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PMID: 16478489
DOI: 10.1111/j.1365-2672.2005.02803.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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