Article
Dual tropism of HIV-1 envelopes derived from renal tubular epithelial cells of patients with HIV-associated nephropathy.
AIDS (London, England) - 28 Feb 2006
Zerhouni-Layachi Bouchra, Husain Mohammad, Ross Michael J, Marras Daniele, Sunamoto Masaaki, Liu Xinyan, Klotman Paul E, Klotman Mary E
Abstract excerpt
The phenotype of HIV-1 gp120 envelope derived from renal epithelium and peripheral blood mononuclear cells (PBMC) of patients with HIV-associated nephropathy was investigated in vitro. Chimeric viruses were derived from kidney or blood and used to infect primary CD4+T cells, cell lines expressing single co-receptors and a renal epithelial cell line HPT-1. HIV-1 variants derived from renal epithelium were dual...
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