Article
Glycan dependent phenotype differences of HIV-1 generated from macrophage versus CD4+ T helper cell populations.
Frontiers in immunology - 1 Jan 2023
Heeregrave Edwin J, Thomas Jordan, van Capel Toni M, de Jong Esther C, Pollakis Georgios, Paxton William A
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) is able to infect a variety of cell types with differences in entry efficiency and replication kinetics determined by the host cell type or the viral phenotype. The phenotype of the virus produced from these various cell types, including infectivity, co-receptor usage and neutralisation sensitivity, may also be affected by the characteristics of the producing cell. This...
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