Article
Certainly can't live without this: SIRT6.
Cell metabolism - 1 Feb 2006
Rodgers Joseph T, Puigserver Pere
Abstract excerpt
Cellular metabolic rates might regulate aging by impinging on genomic stability through the DNA repair pathways. A new study published in Cell (Mostoslavsky et al., 2006) reports that deficiency in one of the mammalian Sir2 homologs, SIRT6, results in genome instability through the DNA base excis...
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