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Article

Constitutive activation of zebrafish Stat5 expands hematopoietic cell populations in vivo.

Experimental hematology - 1 Feb 2006

Lewis Rowena S, Stephenson Sarah E M, Ward Alister C

Abstract excerpt

OBJECTIVE: Constitutive activation of Stat5 has been observed in a variety of malignancies, particularly myeloid leukemias. To directly investigate the in vivo consequences of Stat5 perturbation, we expressed constitutively active forms in zebrafish. METHODS: We generated mutants of the zebrafish...

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Identifiers

PMID: 16459186
DOI: 10.1016/j.exphem.2005.11.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16459186-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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